(Gavin Ritz
2010.02.15.9.49NZT)
[From Bill Powers
(2010.02.14.0515 MST)]
Gavin Ritz 2010.02.14.13.35NZT
GR:
I’m an engineer so I know exactly what a signal is. You use NSU
units in PCT can you point me to the specific texts so I can see what the
relationship is between NSU units and the SI units. That is what is
the conversion factor of impulses per second?
BP:I don’t know: it probably varies with the sensor in question.
This is my point, so in other words PCT as
it stands, is truncated from modern scientific thinking.
GR:
For example I can convert temperature to Joules-1 using the beta
function, so in SI units there are the 7 accepted quantities and energy and all
other variables can be calculated from these seven quantities.
BP: OK, I’ll take your word for it. I knew all that stuff once but mostly just
use the derived units.
You seem to take this so lightly but this
is the crux of the assumptions you make in BCP. “No conservation
of energy”
BP Earlier: It means the
magnitude of a physical quantity like a voltage or
the frequency firing of a neuron.
GR: My
point exactly and this requires energy any signal has an energy requirement
otherwise there will not be a signal.
BP: Of course, but neural signals do not carry energy from one place to
another. That’s not how they work.
Yes okay but energy is required along the
entire nervous system to propagate them via the Na-K ion Pump.
I used the analogy of a
row of dominoes standing on end. A small amount of energy is required to topple
the first domino
No it’s not. Energy is required
along the entire length of the nerves. (Skou 1997)
. The first domino then
is accelerated downward by gravity, losing potential energy and gaining kinetic
energy. At some point it contacts the next domino and exerts the small amount
of force needed to topple it, then it goes on falling until it is overlapping
the next domino on the floor. And so it goes down the row of dominoes.
This machine analogy is 100% incorrect.
That is analogous to the
way a neural impulse gets from one end of the axon to the other.
Okay then how specifically does that
happen?
Actually, it’s an
electrical breakdown phenomenon with the discharge corresponding to a domino
toppling. The discharge of one point along the fiber triggers the discharge of
the next point. The energy required to recharge the membrane capacitance comes
from the fluids outside the axon; that’s like the energy required to stand the
dominos up again in preparation for the next “impulse.” In a nerve
fiber, there is a net loss of energy as the impulse propagates, which has to be
replaced by metabolism to allow the next impulse to propagate.
I’m just not sure how you get to all
this the signals are helped along but the ion pump.
GR: I
used to own a company that manufactured Mercury cadmium telluride semiconductor
so this is an area I know a little about. (Signals and voltage).
BP: For a person with such extensive knowledge and experience, you are having
unaccountable difficulty with understanding me.
Well for one a lot of what you saying just
doesn’t stack up.
BP Earlier: It is called
a signal because the physical variable involved is very weak, not able by
itself to caused any significant physical consequences, but its magnitude
carries information about the magnitude of some other variable that does have
significant physical effects.
GR: How do you know this specifically? Can you point me to the research in
which shows there is only a weak signal? Because as engineers we know that it
takes 0.693kT joules of energy to transmit one bit.
BP: We do not know any such thing. You can transmit one bit of information
without moving any energy from source to destination;
No ones talking about moving energy.
in fact you can transmit
information by draining energy from the destination, returning it to the source
of the information. Telegraphers do that all the time, or did
(there probably aren’t many of them left). I don’t know where you got your
formula – it probably applies to some particular case.
Basic communication theory from Shannon, (Peirce 1963) and no its
specific to transmitting one bit.
Neural signals are propagated by opening and closing channels in the wall of
the fiber to let ions in and out. See
[http://www.biologymad.com/NervousSystem/nerveimpulses.htm
](http://www.biologymad.com/NervousSystem/nerveimpulses.htm)One transfer involves moving three positively charged sodium ions outward,
charging the inside membrane potential to -70 millivolts. Three charges amounts
to 3.8E-19 coulombs so the energy change, the product of charge times
voltage, is 2.6E-20 joules. I don’t know how many transfers are needed to
recharge the membrane locally after the passage of one impulse, but it can’t be
very many, maybe only one. This is why I say the energy involved in neural
impulses is very tiny. “Tiny” doesn’t begin to convey how small it
is.
Well did you actually read this article
that’s the N-K pump and that little red blob is ATP being used up. So it
becomes ADP which is really just the dead husk of an ATP molecule and it’s
converted back to ATP via the ATPase synthase molecule (Walker 1997). This is all an
energy process.
BP earlier: At some point
in a network of signals, there is an amplifier (like a muscle) that transforms
the weak signal into a large physical effect, as the signal from a motor neuron
is transformed into a muscle tension that, in the biceps for example, can exert
a pull of over a quarter of a ton.
That, by the way, is the primary place where metabolic energy is
used – in the transformation from signals to physical effects.
GR: Can
you point me to the specific research which shows the relationship between the
usage of energy in the nervous system and the muscles?
No. Probably someone else can cite a textbook or handbook. Just judging from
the energy requirements for transmitting signals, and the observable muscle
forces acting through normal distances, it’s pretty clear that muscles use
millions of billions of times as much energy as the innervating impulses use.
Well you don’t actually know this.
Even if hundreds of
thousands or millions of impulses are needed to activate a muscle, the muscles
uses immensely more energy than the nerve signals use. That energy comes
from ATP in the intercellular fluids constantly being replenished from the
bloodstream near the muscles.
There are a lot of neurons in the brain; together, they would require a fairly
large expenditure of energy, for metabolism and signal handling, though not
much per neuron. Note that I say “expenditure” of energy. Nerve
activity uses up metabolic energy.
And so does the brain use huge amounts
actually 25% of the body’s energy requirement.
BP earlier: In the
control system, signals are combined by being added to or subtracted from other
signals – in terms of their magnitudes. The reference signal, set to some
steady number of impulses per second (a neural signal, that is), enters a
neural comparator,
GR: Okay so where is the energy coming from to do this. In our last
correspondence you told me it just appears and used the water level and energy
conversion example saying that water is not transformed into electricity and
energy is just a calculation and nothing more.
BP: That’s a pretty garbled version of what I wrote; if that’s what you got
from it I don’t blame you for not understanding it. I don’t either.
Well here it is exactly what you said.”
BP: “Energy is not
a thing or a substance. It’s a calculation.
This tells me a lot how you think about
energy.
BP:”You can
transform the potential energy of water in an elevated reservoir into
electrical energy simply by multiplying the number of foot-pounds by 1.355 times
to get joules or watt-seconds, times an efficiency factor that tells how much
work will be done by the generators against friction and other non-useful
factors.”
This does not mean there
is something in the water that gets into the electricity. The electrical energy
number in joules contains no trace of evidence about where it came from.
What does this mean? If not the interpretation
that I gave it.
BP: “It would be
the same number no matter what its metaphorical source. It’s just a (very
handy) calculation”.
Not too sure that many in the scientific
world would agree with this.
The energy, as I keep
saying, comes from metabolism,
Above you just said that it has no trace
from where it came from, here you say it comes from metabolism.
and has to be supplied to nerves through their membranes from the
surrounding fluids. Stimulation of sensory nerves does not supply
energy; it causes metabolic energy to be used up to transmit the nerve signals.
GR: This
argument I have never heard before.
BP: The way you report what I said, neither have I.
GR: I
think we have a Maxwell Demon situation with your argument here.
BP: Not at all. The energy balance is perfect, as usual in nature.
You
still have not explained how you convert your NSU units into the energy requirements
to generate those NSU units. In communication theory it’s pretty well
established that so much energy is required to transmit one bit. So how much
energy is required to transmit one NSU.
All
the energy needed to transmit neural impulses and to make muscles contract, and
enough more to keep the person alive, is supplied by the food that is eaten and
the air that is breathed by the person.
This doesn’t
answer the specific question.
Regards
Gavin