[From Bill Powers (971217.0929 MST)]
From: David Goldstein
Subject: 12/17/97
Subject: Re: "trying" to do
The strategy which seems to be followed
nowadays is that they try to identify what parts of the brain are
involved in some condition (say OCD) via a brain imaging technique,
then they try to identify the receptors present in the neurons present
in the abnormal areas, and then they select or design a drug which will
alter the concentration of the neurotransmitters active in the area.
Sounds simple enough for any child to understand. And about reasonable enough.
Your rather simplistic statement assumes that giving "medication" never
ameliorates a person's symptoms while making it more difficult to solve
life problems.
I don't think I am assuming this. I know that if a person is
experiencing too severe symptoms, they are unable to work on the life
problems. I have obsevered this in others and experienced it myself. A
person who is drowning, can hang onto a floatation device and learn to
swim or be satisfied with a life of hanging onto the floatation device,
if that is his choice. Do you think it is right to withhold the
floatation device if you have one?
I said I agreed that in extreme cases, using drugs can make it more
possible for a person to solve some problems. But it's a desperation
measure, because you haven't the slightest idea of what you're actually
doing to the person's brain. This process is like giving a child a
soldering iron and turning him loose on a mainframe computer.
I
think it is irresponsible to make the blanket assumption that "chemical
imbalances" are causes rather than effects.
If giving a person a drug, reduces error signals, it seems reasonable
to assume that a person is being moved closer to some reference
condition. Are not reference conditions one of the independent
variables(causes)?
Relative to a single control system, yes. In the whole brain, no. What sets
reference signals? What if the reference signal is set so there is a
conflict with satisfying some other reference condition? What if the
problem is not the error signal, but an unresponsive output function? What
if the perceptual signal no longer represents the lower-order world in a
way consistent with other perceptions? Who says that the reference signal
is set where it ought to be for the good of the whole system? Who says
you're even looking at the right problem?
There's a condition which some old people get that is very dangerous. They
lose the ability to feel pain in their limbs. As a result they can injure
themselves very seriously and not notice the injury until it has become
infected, or caused a major loss of blood. So is arbitrarily correcting
error signals without correcting the condition that is causing them really
a good idea? I would say it is to be avoided at almost all costs -- the
only exception being when the error signal is so large that it's preventing
any other effective actions.
I think you have to consider very carefully what you are buying time FOR.
If a person is in intractable pain, at best you're buying time to live in a
drug-induced stupor for a little longer. If that's what the person wants,
OK, but what if it's not? It's easy to say that there's something wrong
with the person's brain because his preferences differ from yours. In fact,
that's the general medical assumption, isn't it? Doctor knows best. Anyone
who disagrees must have a damaged brain.
I actually agree that there is a case for assisted suicide. We have to
proceed very carefully. There are a many people who would object on
religious grounds.
If it's their own suicide they're rejecting on such grounds, you'll hear no
objection from me. But that's not a decision they can make for anyone else.
About the therapy strategy in Brainlocked, Bill says:
Why should this approach have any effect if the real problem is a chemical
imbalance in the brain? If all deviant behavior is caused by a surplus or a
deficit in certain neurotransmitters, what is the point of encouraging a
person to change his awareness or tell things to himself? Words and
thoughts are just secretions of the brain; when the brain is set right
chemically, the proper words and thoughts will result. Isn't that pretty
much the medical view?
In the case of OCD, the effective drugs seem to involve the
neurotransmitter Serotonin. People with OCD say that the drug helps
them to follow this strategy. If the urge is too strong, they find it
hard to ignore the obsession or compulsion. Some people say things like
my mind is not strong enough to ignore the symptoms. The symptoms are
exhausting. They reach a point in which suicide ideas occurs.
Could you come up with a list of all the disorders that "involve"
serotonin? Serotonin is just a neurotransmitter; it is part of the process
of neural computation, and has nothing to do with the _meaning_ of any
particular computation. Implicating seretonin is like implicating a
shortage or excess of electrons in a computer bug. Such a shortage or
excess is certainly involved, but it's not the cause of the problem -- the
problem is that the program is setting ones where it should be setting
zeros or vice versa. If you found an overheating resistor in a radio, would
you fix the problem by installing a fan to blow on it?
Even if seretonin were involved in the operation of only one part of the
brain (which is not true), a part big enough to see in a brain scan
probably is made of millions of neurons, which are performing hundreds or
thousands of different kinds of computations. How do you know whether the
software or the hardware is defective? How do you know that the change in
seretonin level is not part of an attempt to correct an error that's being
caused elsewhere?
>Schwartz, a psychiatrist at UCLA, found that this therapy produced the
>same changes in the brain as measured by PET scan.
The same changes as what? You forgot to say.
There is a decrease in activity in the orbital frontal cortex and the
caudate nucleus, and a decrease in the degree of coupling in these
areas.
You still didn't say what the change is the same as. The change produced by
a pure drug treatment? Some other form of therapy? The PET scan just tells
you where there is activity. It doesn't tell you what the activity is
doing, or whether a change is good or bad for the person.
>He looks at the role
>of medication as helping a person find it easier to do the above
>program. He sees that this program helps a person develop a mindfulness,
>increased self-awarenes which he calls the Impartial Spectator. In PCT,
>we might say that a person is going up from the program or principle
>level to the system level self-image systems.
You might say that, but on what basis? The "Impartial Spectator" sounds
like what we have called the Observer, in the Method of Levels. But how
could disturbing the chemical systems that support brain activity have any
such specific effects? This sort of empty theorizing doesn't impress me at
all. It impresses me all the less when it's expressed in pseudo-PCT terms.
The content of the OCD symptoms seems to be unimportant.
That's what people say when they don't understand what is going on. If they
don't understand it, it must be unimportant.
Previous
therapy attempts which addressed the specific content go no place. A
person keeps on repeating and repeating and repeating. Saying things
like: It is a false alarm. It is my OCD. helps a person do something
very difficult. It is very difficult to ignore an error signal. If one
comes to believe that the error signal is false, one may be willing,
able to ignore it.
Fine. How does a drug instil that understanding? And whose previous therapy
attempts were considered?
But this is also an argument against indiscriminate drug treatment. If you
remove (by ANY means) the signals that drive reorganization, reorganization
is less likely to occur. And because the effects of drugs are not dependent
on behavior, there is no reason to expect any reorganization that does
occur to be relevant to the experienced problem -- which is no longer being
experienced because the drugs have suppressed it. In talking therapies, we
encourage clients to experience the distress and see how it relates to the
way they think and live. Would you give a client suffering from anxiety a
drug that removes the capacity to feel anxiety? If you just wanted to
relieve the symptom, of course you would. But if you wanted this person to
reorganize so that anxiety no longer occurred, you would have prevented any
useful progress in that direction.
In the case of OCD, the anxiety is not useful, functional.
How the hell do you know that? Are you saying that returning to your house
to see if you shut off the gas is not useful or functional?
A person
temporarily relieves it by compulsing. As mentioned above, the content
is not important. A person may get over one obsession/compulsion at one
time only to have a different one appear at a later time.
But you were just describing a treatment that involved saying things to
yourself, learning to perceive the OCD process differently, and so on. If
all problems are caused by chemical imbalances, what possible effect could
such software solutions have? You seem to be believing two contradictory
arguments at once.
If you are prepared to offer a warrantee stating that the person will in
fact be better off by staying alive, then you have some excuse for
preventing suicide. I suggest a $100,000 bond, secured by your house, to be
paid in case the client finds that life is no more tolerable than before.
After all, you are risking only money, while the client, in agreeing to
stay alive, is risking something so distasteful that death seems a
preferable alternative.
Do you really think that all suicides are alike?
A person always has the opportunity to suicide. As I mentioned, I
think there is a case for assisted suicide. I have known people who
have wanted to suicide but were glad that they were stopped. In a
sense, suicide is the ultimate drug. All error signals are reduced to
zero without further efforts. At least with drugs, one does not throw
out the baby with the bathwater.
Nor does one separate those who would benefit from intervention from those
one cannot help. If all you're concerned about is your own track record as
a therapist, then you're safe in giving the drugs; all you nee3d is for the
successes to outweigh the failures. Then you need to remember only the
successes. But if you had a stake in the outcome equal to that of the
person you're dealing with, you might not be so sure you were right in any
individual case. That's why I mentioned the warrantee. If you can't go by
the Hippocratic principle (First, do no harm), then perhaps you might go
for a monetary principle (First, don't go broke).
Best,
Bill P.